Nat Immunol. 2011 Jan;12(1):12-4. doi: 10.1038/ni0111-12.
NF-κB is a critical transcription factor that is regulated by several post-transcriptional modifications. The characterization of their roles would help in the design of new therapeutic targets in cancer and inflammation.
NF-κB 是一种关键的转录因子,受多种转录后修饰调控。它们的作用特征有助于设计癌症和炎症的新治疗靶点。