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烟酸缓释剂(ER)/辛伐他汀(Simcor®):在血脂调节中的应用指南。

Niacin extended release (ER)/simvastatin (Simcor®): a guide to its use in lipid regulation.

机构信息

Adis, a Wolters Kluwer Business, Auckland, New Zealand.

出版信息

Drugs R D. 2010;10(4):253-60. doi: 10.2165/11202560-000000000-00000.

Abstract

Oral fixed-dose niacin extended release/simvastatin is associated with clinically relevant improvements in plasma lipid profiles, including lowering of non-high-density lipoprotein cholesterol levels, relative to simvastatin monotherapy in patients with mixed dyslipidemias who had not responded fully to simvastatin monotherapy, and is generally well tolerated.

摘要

口服固定剂量烟酸缓释/辛伐他汀与辛伐他汀单药治疗相比,可使混合性血脂异常患者的血脂谱得到临床相关改善,包括降低非高密度脂蛋白胆固醇水平,这些患者对辛伐他汀单药治疗反应不完全,且通常具有良好的耐受性。

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The mechanism and mitigation of niacin-induced flushing.
Int J Clin Pract. 2009 Sep;63(9):1369-77. doi: 10.1111/j.1742-1241.2009.02099.x.

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