Divison of Rehabilitation Medicine, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.
J Rehabil Med. 2011 Jan;43(1):39-45. doi: 10.2340/16501977-0634.
To examine the characteristics of fatigued and non-fatigued post-polio patients and to define potential subgroups across the fatigue continuum.
Multi-centre study.
A total of 143 post-polio patients were subdivided on the basis of percentile distribution into a fatigue group, a intermediate group, and a non-fatigue group, using the Multi Fatigue Inventory 20 general fatigue ratings.
Data on background, quality of life, fatigue and pain were collected. Descriptive statistics and correlations in each group and analysis of variance and χ2 for group comparisons were performed. Non-linear regressions were employed to evaluate differences in the strength of associations between physical and mental fatigue, on the one hand, and vitality on the other.
The fatigued group was younger, had shorter polio duration, more pain, higher body mass index, lower quality of life and was more physically and mentally fatigued. A higher proportion of this group had contracted polio after 1956 and was under 65 years of age. Mental fatigue had a relatively higher explanatory value than physical fatigue for differences in vitality in the fatigued group, whereas reversed patterns were seen in the other groups.
Fatigued post-polio patients can be considered as a subgroup.
研究疲劳和非疲劳性肌萎缩侧索硬化症患者的特点，并确定疲劳连续体中的潜在亚组。
多中心研究。
共有 143 名肌萎缩侧索硬化症患者，根据百分位分布，使用多疲劳量表 20 项一般疲劳评分，分为疲劳组、中间组和非疲劳组。
收集背景、生活质量、疲劳和疼痛的数据。对每组进行描述性统计和相关性分析，并进行方差分析和 χ2 组间比较。采用非线性回归评估体力和脑力疲劳与活力之间的关联强度差异。
疲劳组年龄较小，患肌萎缩侧索硬化症时间较短，疼痛较多，体重指数较高，生活质量较低，体力和脑力疲劳程度较高。该组中更多的人是在 1956 年后感染脊髓灰质炎，且年龄在 65 岁以下。在疲劳组中，精神疲劳对活力差异的解释力高于体力疲劳，而在其他组中则出现相反的模式。
疲劳性肌萎缩侧索硬化症患者可以被视为一个亚组。
