Kluge K, Grasshoff H, Weise E M, Weickert H
Klinik für Orthopädie, Medizinischen Akademie Magdeburg.
Beitr Orthop Traumatol. 1990 Apr;37(4):207-10.
Since 1984 the perioperative prophylaxis was carried out using the antibiotics Oxacillin or Halospor in artificial joint replacement of the hip. We started with 1 g Oxacillin at the very beginning of the anaesthesie. Further 0.5 g Oxacillin were administered 2 and 6 hours later. 964 hip joints operated between 1982-1988 were followed up. We observed a marked decrease of the rate of infection from 7.2% to 1.0% after the introduction of the perioperative prophylaxis.
自1984年起,在髋关节人工关节置换术中使用抗生素苯唑西林或哈洛孢菌素进行围手术期预防。我们在麻醉开始时首先给予1克苯唑西林,然后在2小时和6小时后再分别给予0.5克苯唑西林。对1982年至1988年间进行手术的964个髋关节进行了随访。我们观察到,引入围手术期预防措施后,感染率从7.2%显著下降至1.0%。