纯网织红细胞脂氧合酶形成加氧酶和氢过氧化物酶产物。
Formation of oxygenase and hydroperoxidase products by the pure reticulocyte lipoxygenase.
作者信息
Kühn H, Wiesner R, Schewe T
机构信息
Institute of Biochemistry, School of Medicine (Charité), Humboldt University, Berlin, GDR.
出版信息
Biomed Biochim Acta. 1990;49(2-3):S39-41.
The pure reticulocyte lipoxygenase oxygenates free arachidonic acid to 15S- and 12S-HPETE in a ratio of about 10:1 15S-H(P)ETE or its methyl ester can be further converted by the lipoxygenase via three different types of reactions: (i) oxygenase reaction, (ii) hydroperoxidase reaction and (iii) leukotriene synthase reaction. Here we summarize the products formed from arachidonic acid by the reticulocyte lipoxygenase via these three types of reactions.
纯网织红细胞脂氧合酶将游离花生四烯酸氧化为15S-和12S-氢过氧化二十碳四烯酸（HPETE），其比例约为10:1。15S-H(P)ETE或其甲酯可通过脂氧合酶经由三种不同类型的反应进一步转化：（i）加氧酶反应，（ii）氢过氧化物酶反应和（iii）白三烯合酶反应。在此，我们总结网织红细胞脂氧合酶通过这三种类型反应由花生四烯酸形成的产物。
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