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尼日利亚东南部一家三级中心子痫的临床表现与结局——一项为期6年的回顾

Presentation and outcome of eclampsia at a tertiary center in South East Nigeria--a 6-year review.

作者信息

Eke Ahizechukwu Chigoziem, Ezebialu Ifeanyichukwu Uzoma, Okafor Charles

机构信息

Department of Obstetrics and Gynecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.

出版信息

Hypertens Pregnancy. 2011;30(2):125-32. doi: 10.3109/10641955.2010.525283. Epub 2010 Dec 21.

Abstract

OBJECTIVE

To determine the maternal and fetal outcomes of eclamptic patients treated in Nnamdi Azikiwe University Teaching Hospital, Nnewi, over a 6-year period (2004-2009).

MATERIALS AND METHODS

It was a retrospective study. The case notes of 212 patients with eclampsia were analyzed with respect to age, parity, type of eclampsia, gestational age, booking status, mode of delivery, and outcome of the babies and mothers.

RESULTS

There were 212 cases of eclampsia out of a total of 13,536 deliveries, giving a prevalence of 1.57%. One hundred and sixty (24.5%) of the women were unbooked. Antepartum eclampsia constituted 160 (75.5%) of all types of eclampsia. Nulliparous teenagers were the most commonly affected women--128 (60.4%). Cesarean delivery was higher than vaginal delivery, accounting for 160 (75.5%) of all deliveries. There was a statistically significant relationship between the route of delivery and the parity of the women (χ(2) = 3.60; d = 5; p = 0.035). There were 16 maternal deaths, giving a case fatality rate of 7.5%. There were 12 neonatal and 8 perinatal deaths. Puerperal sepsis occurred in 9.4% of the patients.

CONCLUSION

Eclampsia is a major cause of maternal mortality in Nnewi, rural South East Nigeria. Teenage nulliparous women are most susceptible.

摘要

目的

确定在阿齐克韦大学教学医院(位于尼日利亚东南部城市纽维)接受治疗的子痫患者在6年期间(2004 - 2009年)的母婴结局。

材料与方法

这是一项回顾性研究。分析了212例子痫患者的病历,内容包括年龄、产次、子痫类型、孕周、登记情况、分娩方式以及母婴结局。

结果

在总共13536例分娩中,子痫患者有212例,患病率为1.57%。160名(24.5%)女性未进行产前登记。产前子痫占所有子痫类型的160例(75.5%)。初产青少年是最常受影响的女性群体——128例(60.4%)。剖宫产率高于阴道分娩率,占所有分娩的160例(75.5%)。分娩方式与女性产次之间存在统计学显著关系(χ(2)=3.60;自由度=5;p = 0.035)。有16例孕产妇死亡,病死率为7.5%。有12例新生儿死亡和8例围产儿死亡。9.4%的患者发生了产褥期感染。

结论

子痫是尼日利亚东南部农村地区纽维孕产妇死亡的主要原因。初产青少年女性最易患病。

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