Uemoto Shinji
Department of Surgery, Division of Hepato-Pancreato-Biliary Surgery, Kyoto University Graduate School of Medicine.
Nihon Rinsho. 2010 Dec;68(12):2277-80.
Living donor liver transplantation (LDLT) had been started for pediatric patients since 1989, and indication of LDLT has been expanded to adult patients in concomitance with overcoming small-for-size graft. Recently, around 500 cases of LDLT have been performed annually, and outcome of pediatric patients after LDLT has been improved with more than 90% of patient survival rate. Deceased donor liver transplantation (DDLT) also had been started since 1999, however, annual number of DDLT remained less than 10 cases. Therefore, condition of liver transplantation in Japan is quite unique, which consist of more than 98% of LDLT and less than 2% of DDLT. Law of organ transplantation had been modified in July 2010, which had been changed to world standard one.
自1989年起，活体供肝肝移植（LDLT）就已应用于儿科患者，随着小体积移植物问题的攻克，LDLT的适应证已扩展至成年患者。近年来，每年约有500例LDLT手术实施，儿科患者LDLT术后的结局得到改善，患者生存率超过90%。尸体供肝肝移植（DDLT）自1999年起也已开展，然而，每年DDLT的例数仍不足10例。因此，日本的肝移植情况颇为独特，其中LDLT占比超过98%，DDLT占比不到2%。2010年7月，器官移植法进行了修订，已与国际标准接轨。
