英夫利昔单抗有助于肛门克罗恩病患者肛门节制功能的恢复。

Infliximab aids recovery of anal continence in a patient with perianal Crohn's disease.

机构信息

Gastroenterology Service, Centro Hospitalar do Porto-Hospital Geral de Santo António, Porto, Portugal.

出版信息

BioDrugs. 2010 Dec 14;24 Suppl 1:22-4. doi: 10.2165/11586270-000000000-00000.

Abstract

Perianal complications occur in approximately 33% of patients with Crohn's disease, and may be the most prominent or even the presenting complaint suggestive of a diagnosis of Crohn's disease. A case is reported of severe perianal Crohn's disease with anal destruction and incontinence that developed after perianal surgery. Healing of perianal lesions and recovery of anal function was achieved with infliximab therapy.

摘要

肛周并发症发生于约 33%的克罗恩病患者，可能是最突出的表现，甚至是提示诊断克罗恩病的首发症状。报告 1 例肛周克罗恩病患者，在外周手术后出现严重的肛周病变、肛门破坏和失禁。英夫利昔单抗治疗使肛周病变愈合，肛门功能恢复。