脐带血：现状与未来方向。

Umbilical cord blood: current status and future directions.

机构信息

Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota, Saint Paul, MN 55108, USA.

出版信息

Vox Sang. 2011 Jan;100(1):150-62. doi: 10.1111/j.1423-0410.2010.01409.x.

DOI:10.1111/j.1423-0410.2010.01409.x

PMID:21175665

Abstract

Once considered biological waste, umbilical cord blood (UCB) has become an accepted source of haematopoietic stem cells (HSCs). With initial success in the pediatric setting, UCB transplantation continues to gain favor in the adult patient population. Novel approaches to UCB transplantation include use of two units and a variety of graft manipulations. Additional uses for UCB are currently being explored and include applications in regenerative medicine and immunotherapy.

摘要

曾经被认为是生物废物的脐带血（UCB）已成为造血干细胞（HSCs）的公认来源。在儿科领域取得初步成功后，UCB 移植在成年患者群体中继续受到青睐。UCB 移植的新方法包括使用两个单位和各种移植物处理。目前正在探索 UCB 的其他用途，包括在再生医学和免疫疗法中的应用。