新西兰野生绵羊中具有潜在经济重要性的选定基因的遗传多样性。
Genetic diversity of selected genes that are potentially economically important in feral sheep of New Zealand.
机构信息
Department of Agricultural Science, Faculty of Agriculture and Life Sciences, PO Box 84, Lincoln University, Lincoln 7647, New Zealand.
出版信息
Genet Sel Evol. 2010 Dec 21;42(1):43. doi: 10.1186/1297-9686-42-43.
BACKGROUND
Feral sheep are considered to be a source of genetic variation that has been lost from their domestic counterparts through selection.
METHODS
This study investigates variation in the genes KRTAP1-1, KRT33, ADRB3 and DQA2 in Merino-like feral sheep populations from New Zealand and its offshore islands. These genes have previously been shown to influence wool, lamb survival and animal health.
RESULTS
All the genes were polymorphic, but no new allele was identified in the feral populations. In some of these populations, allele frequencies differed from those observed in commercial Merino sheep and other breeds found in New Zealand. Heterozygosity levels were comparable to those observed in other studies on feral sheep. Our results suggest that some of the feral populations may have been either inbred or outbred over the duration of their apparent isolation.
CONCLUSION
The variation described here allows us to draw some conclusions about the likely genetic origin of the populations and selective pressures that may have acted upon them, but they do not appear to be a source of new genetic material, at least for these four genes.
背景
野生绵羊被认为是遗传变异的来源，这些变异在经过选择后从其家养绵羊中丢失了。
方法
本研究调查了来自新西兰及其近海岛屿的类似于美利奴羊的野生绵羊群体中 KRTAP1-1、KRT33、ADRB3 和 DQA2 基因的变异情况。这些基因先前已被证明会影响羊毛、羔羊存活率和动物健康。
结果
所有基因都是多态的，但在野生种群中没有发现新的等位基因。在这些种群中的一些中，等位基因频率与商业美利奴绵羊和新西兰其他品种观察到的频率不同。杂合度水平与其他关于野生绵羊的研究相似。我们的研究结果表明，在它们明显隔离的过程中，一些野生种群可能存在近交或远交。
结论
这里描述的变异使我们能够对这些种群的可能遗传起源和可能对它们施加的选择压力得出一些结论，但它们似乎不是新遗传物质的来源，至少对于这四个基因而言是这样。
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