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对青春期产科患者进行性传播感染的重复筛查。

Repeat screening for sexually transmitted infection in adolescent obstetric patients.

作者信息

Aggarwal Anjali, Spitzer Rachel F, Caccia Nicolette, Stephens Derek, Johnstone Joley, Allen Lisa

机构信息

Department of Obstetrics and Gynaecology, University of Toronto, Toronto, ON, USA.

出版信息

J Obstet Gynaecol Can. 2010 Oct;32(10):956-61. doi: 10.1016/s1701-2163(16)34683-7.

Abstract

OBJECTIVE

To determine if repeat screening for sexually transmitted infection is appropriate for adolescent obstetric patients and to identify any risk factors associated with increased risk of contracting a sexually transmitted infection (STI) during pregnancy.

METHODS

We conducted a retrospective review of the medical records of adolescent obstetric patients seen over a five-year period in the Young Prenatal Program at the Hospital for Sick Children (Toronto, Ontario).

RESULTS

Between January 2003 and December 2007, 201 patients with 211 pregnancies attended the Young Prenatal Program. Of the 211 pregnancies reviewed, all patients had screening at baseline for HIV, syphilis, hepatitis B, chlamydia, gonorrhea, and trichomonas; 173 patients were screened in the third trimester, two were tested at another point in the pregnancy because of symptoms, and 161 were screened at their postpartum visit. In 53 pregnancies, STI was diagnosed either during pregnancy or postpartum. Fourteen patients had multiple sexually transmitted infections for a total of 71 infections. Thirty-four infections were diagnosed at baseline, 15 in the third trimester, two because of symptoms, and seven were diagnosed postpartum. In patients who did not develop an STI during pregnancy, the previous use of contraception (excluding condoms), being in a relationship with the baby's father, and living with their partner were identified as significant protective factors against STI. There was a trend towards significance for contracting an STI in patients with a history of abuse, in those with a higher than average number of sexual partners, and in those with a younger than average age of coitarche.

CONCLUSION

Sexually transmitted infections were diagnosed in 25.1% of adolescent pregnancies (53/211) in our cohort. Of the 71 sexually transmitted infections diagnosed, 22.5% (16/71) were diagnosed on routine third trimester screening. Because of the high rates of STI and the small number of identified risk factors, routine repeat screening in the third trimester for chlamydia, gonorrhea, and trichomonas is warranted in pregnant adolescents.

摘要

目的

确定对青春期产科患者进行性传播感染重复筛查是否合适,并识别孕期感染性传播感染(STI)风险增加的相关危险因素。

方法

我们对多伦多病童医院青年产前项目在五年期间诊治的青春期产科患者的病历进行了回顾性研究。

结果

2003年1月至2007年12月,201例患者的211次妊娠参加了青年产前项目。在审查的211次妊娠中,所有患者在基线时均接受了艾滋病毒、梅毒、乙型肝炎、衣原体、淋病和滴虫的筛查;173例患者在孕晚期接受了筛查,2例因出现症状在孕期其他时间进行了检测,161例在产后访视时接受了筛查。在53次妊娠中,孕期或产后诊断出STI。14例患者患有多种性传播感染,共71次感染。34次感染在基线时被诊断出,15次在孕晚期,2次因症状,7次在产后被诊断出。在孕期未发生STI的患者中,既往使用避孕措施(不包括避孕套)、与婴儿父亲保持恋爱关系以及与伴侣同住被确定为预防STI的重要保护因素。有虐待史、性伴侣数量高于平均水平以及初次性交年龄低于平均水平的患者感染STI有显著趋势。

结论

在我们的队列中,25.1%(53/211)的青春期妊娠诊断出性传播感染。在诊断出的71次性传播感染中,22.5%(16/71)在常规孕晚期筛查时被诊断出。由于STI发病率高且识别出的危险因素较少,对怀孕青少年在孕晚期常规重复筛查衣原体、淋病和滴虫是必要的。

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