Tao Duo-duo, Chen Bing, Wang Zheng-min, Chi Fang-lu, Li Hua-wei
Department of Otology and Skull Base Surgery, Fudan University, Shanghai 200031, China.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2010 Oct;45(10):824-9.
To evaluate the effect of cochlear implantation with REZ-I straight electrodes on residual hearing of postlingually deafened adults, and to explore the audiologically safety and injury characteristics of cochlear implantation.
Sixteen unilateral REZ-I (22 channels) cochlear implantation recipients from September 2009 to December 2009 were picked out. Their pre-and post-implantation audiometry data including pure-tone audiometry (PTA), auditory steady-state responses (ASSR), auditory brainstem responses (ABR) and distortion product otoacoustic emissions (DPOAE) were retrospectively analyzed, in order to compare the change between pre- and post-implantation residual hearing.
Among the 12 recipients who had some measurable residual hearing before implantation, 5 (41.6%) patients had conserved some measurable hearing but the other 7 (58.4%) recipients had lost all measurable hearing after implantation on the implanted side. The implanted ears had an average PTA threshold drop of 9.5 dB HL and a statistically significant difference between pre- and post-implantation (P < 0.05) PTA thresholds in the frequencies of 250 Hz, 500 Hz, 1000 Hz, 2000 Hz and 4000 Hz. Compared to non-implanted ears, the drop in 500 Hz and 1kHz had a statistically significant difference between pre- and post-implantation PTA thresholds (P < 0.05). The ASSR residual hearing threshold elevation were statistically significant (P < 0.05) between pre- and post-implantation ASSR at 250 Hz and 500 Hz on the implanted side, while the The ASSR residual hearing threshold elevation were statistically significant (P < 0.05) at 500 Hz when compared to non-implanted side. The difference of residual hearing between pre- and post-implantation was not statistically significant for both DPOAE and ABR.
There will be a certain degree of damage to residual hearing of the implanted side following REZ-I cochlear implantation.
评估使用REZ-I直电极进行人工耳蜗植入对语后聋成人残余听力的影响，并探讨人工耳蜗植入的听力学安全性及损伤特点。
选取2009年9月至2009年12月期间16名单侧接受REZ-I（22通道）人工耳蜗植入的患者。回顾性分析其植入前后的听力测试数据，包括纯音听力测试（PTA）、听觉稳态反应（ASSR）、听觉脑干反应（ABR）和畸变产物耳声发射（DPOAE），以比较植入前后残余听力的变化。
在植入前有可测量残余听力的12名患者中，5名（41.6%）患者保留了一些可测量的听力，但另外7名（58.4%）患者在植入后植入侧失去了所有可测量的听力。植入耳的平均PTA阈值下降了9.5 dB HL，在250 Hz、500 Hz、1000 Hz、2000 Hz和4000 Hz频率下，植入前后的PTA阈值差异有统计学意义（P < 0.05）。与未植入耳相比，500 Hz和1kHz频率下植入前后的PTA阈值下降差异有统计学意义（P < 0.05）。植入侧在250 Hz和500 Hz频率下，植入前后ASSR残余听力阈值升高有统计学意义（P < 0.05），而与未植入侧相比，500 Hz频率下ASSR残余听力阈值升高有统计学意义（P < 0.05）。DPOAE和ABR植入前后的残余听力差异无统计学意义。
REZ-I人工耳蜗植入后，植入侧的残余听力会受到一定程度的损害。
