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[中国近5年眼底疾病诊疗技术的最新进展]

[Up-to-date development of diagnosis and treatment technology of ocular fundus diseases in the past 5 years in China].

作者信息

Li Xiao-xin, Zhao Ming-wei

机构信息

Department of Ophthalmology, Peking University People's Hospital, Beijing 100044, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2010 Oct;46(10):900-5.

Abstract

In the past 5 years, the diagnosis and management of ocular fundus diseases in China has been improved remarkably. Up-to-date international concepts of diagnosis and management, methods, and equipment have been introduced into China, which have promoted the therapeutic technology of ocular fundus diseases. In the field of diagnosis, the application of frequency-domain optical coherence tomography and fundus autofluorescence detection technology not only provided more detailed image information for clinical diagnosis, but also helped clinical ophthalmologists to understand the features and pathogenesis of ocular fundus diseases comprehensively, leading the doctors into a new era of examination of ocular fundus diseases. In the field of treatment, Chinese researchers actively performed innovative clinical studies, such as organizing domestic multi-center studies of various therapies of macular hole retinal detachment, developing full-length humanized antibody fusion protein KH902 with intellectual property rights, using implants of autologous retinal pigment epithelium patch with Bruch membrane to treat age-related macular degeneration, using photodynamic therapy to treat central serous chorioretinopathy, 20 gauge small incision vitrectomy and surgical therapy of central retinal artery occlusion, etc. Moreover, certain amounts of high quality clinical papers have been published in SCI journals, which showed that clinical research of ocular fundus diseases in China has entered the field of international ophthalmology and has geared to international standards.

摘要

在过去5年里,中国眼底疾病的诊断与治疗水平有了显著提高。最新的国际诊断与治疗理念、方法及设备已引入中国,推动了眼底疾病治疗技术的发展。在诊断领域,频域光学相干断层扫描和眼底自发荧光检测技术的应用不仅为临床诊断提供了更详细的图像信息,还帮助临床眼科医生全面了解眼底疾病的特征和发病机制,引领医生进入眼底疾病检查的新时代。在治疗领域,中国研究人员积极开展创新性临床研究,如组织国内多中心黄斑裂孔性视网膜脱离各种治疗方法的研究、研发具有自主知识产权的全长人源化抗体融合蛋白KH902、采用带Bruch膜的自体视网膜色素上皮片植入治疗年龄相关性黄斑变性、运用光动力疗法治疗中心性浆液性脉络膜视网膜病变、20G小切口玻璃体切除术及视网膜中央动脉阻塞的手术治疗等。此外,一定数量的高质量临床论文发表在SCI期刊上,这表明中国眼底疾病的临床研究已进入国际眼科领域并与国际标准接轨。

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