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Suicide activation in a 5-fluorouracil resistant colon cancer model in vitro.

作者信息

Mader R M, Kalipciyan M, Ohana P, Hochberg A, Steger G G

机构信息

Dept.of medicine 1, Medical University of Vienna, Department of Clinical Oncology, Währinger Gürtel 18 – 20, 1090 Vienna, Austria.

出版信息

Int J Clin Pharmacol Ther. 2011 Jan;49(1):69-70.

PMID:21176733
Abstract
摘要

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Treatment of human tumor cells by combine gene therapy harnessing plasmids expressing human tumor necrosis factor alpha and bacterial cytosine deaminase suicide gene.利用表达人肿瘤坏死因子α的质粒和细菌胞嘧啶脱氨酶自杀基因的联合基因疗法治疗人肿瘤细胞。
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Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2025 Mar-Apr;17(2):e70010. doi: 10.1002/wnan.70010.
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A Brief Introduction to Current Cancer Gene Therapy.当前癌症基因治疗简介。
Methods Mol Biol. 2022;2521:1-21. doi: 10.1007/978-1-0716-2441-8_1.
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Safety and efficacy of suicide gene therapy with adenosine deaminase 5-fluorocytosine silmutaneously in in vitro cultures of melanoma and retinal cell lines.
腺嘌呤脱氨酶-5-氟胞嘧啶自杀基因联合治疗对黑色素瘤和视网膜细胞系体外培养的安全性和疗效。
J Cancer. 2014 Apr 17;5(5):368-81. doi: 10.7150/jca.9147. eCollection 2014.
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Suicide Gene Therapy for Cancer - Current Strategies.癌症的自杀基因疗法——当前策略
J Genet Syndr Gene Ther. 2013 Aug 9;4. doi: 10.4172/2157-7412.1000139.