Bernstein J M, Goswami S, Marom Z
Department of Speech-Language and Audiology, State College of New York, Buffalo.
Otolaryngol Head Neck Surg. 1990 Jul;103(1):1-9. doi: 10.1177/019459989010300101.
Macrophage (monocyte)-derived secretagogue (MMS) is a low molecular weight peptide released by activated macrophages. This substance can enhance incorporation of carbohydrates into protein and result in the production of glycoproteins. It is believed that increased glycoproteins lead to the increased tenaciousness of mucoid effusions. Sixteen of 28 middle ear effusions demonstrated significant amounts of MMS. It is suggested that MMS is produced by activated macrophages in MEE and may lead to the development of glycoprotein by secretory epithelial cells. This substance may lead to the development of the mucoid effusion in otitis media with effusion in children.
巨噬细胞（单核细胞）衍生促分泌素（MMS）是一种由活化巨噬细胞释放的低分子量肽。这种物质可增强碳水化合物向蛋白质的掺入，并导致糖蛋白的产生。据信，糖蛋白增加会导致黏液样渗出物的黏性增加。28例中耳积液中有16例显示出大量的MMS。提示MMS由中耳积液中的活化巨噬细胞产生，并可能由分泌上皮细胞导致糖蛋白的形成。这种物质可能导致儿童渗出性中耳炎中黏液样积液的形成。
