Laboratory of Molecular Biology (affiliated with The University of Gdańsk), Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Kładki 24, 80-822 Gdańsk, Poland.
J Gen Virol. 2011 Apr;92(Pt 4):997-1003. doi: 10.1099/vir.0.027326-0. Epub 2010 Dec 22.
Bacteriophage T4 is able to adjust its development to the growth parameters of the host cell. Here, we present evidence for the production of two different subpopulations of phage particles, which differ in their ability to infect starved Escherichia coli cells. The ability of phage T4 to produce a fraction of virions unable to infect starved cells is linked to the functions of genes rI and rIII, as well as rIIA. This may represent the adaptation of phage T4 in order to persist in unfavourable environmental conditions.
噬菌体 T4 能够根据宿主细胞的生长参数来调整其发育。在这里，我们提供了证据表明噬菌体颗粒会产生两种不同的亚群，它们在感染饥饿的大肠杆菌细胞的能力上有所不同。噬菌体 T4 产生一部分无法感染饥饿细胞的病毒粒子的能力与基因 rI、rIII 和 rIIA 的功能有关。这可能代表了噬菌体 T4 为了在不利的环境条件下生存而进行的适应。
