[急性力竭运动对大鼠回肠肌间神经丛胃肠传输速率及氮能神经的影响]
[Effect of acute exhaustive exercise on gastrointestinal transit rate and nitrergic nerves in myenteric plexus in rats ileum].
作者信息
Lei Ya-ning, Ding You-mei
机构信息
Department of Histology and Embryology, Wenzhou Medical College, Wenzhou 325035, China.
出版信息
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2007 May;23(2):218-20.
AIM
To investigate the effect of acute exhaustive exercise on gastrointestinal motility and its enteric nervous mechanisms.
METHODS
24 rats were randomly divided into control group (C) and acute exhaustive exercise group (AEE). The rate of gastrointestinal transit was measured and histologic changes of nitriergic nerves in ileum myenteric plexus were observed with enzymatic histochemical and image analytic technique.
RESULTS
In the rats of AEE group, the rate of gastrointestinal transit was delayed comparing with C group (P < 0.05), the numbers of nitrergic neurons and expression levels of nitric oxide synthase (NOS) in the ileum myenteric plexus significantly increased comparing with C group (P < 0.01).
CONCLUSION
It is possible that increase of nitrergic neurons and expression levels of NOS in the myenteric plexus of small intestine are one of the mechanisms of delay of gastrointestinal transit rate in acute exhaustive exercise rats.
目的
探讨急性力竭运动对胃肠动力及其肠神经机制的影响。
方法
将24只大鼠随机分为对照组（C组）和急性力竭运动组（AEE组）。采用酶组织化学和图像分析技术测量胃肠传输速率，并观察回肠肌间神经丛中氮能神经的组织学变化。
结果
AEE组大鼠的胃肠传输速率较C组延迟（P<0.05），回肠肌间神经丛中氮能神经元数量及一氧化氮合酶（NOS）表达水平较C组显著增加（P<0.01）。
结论
小肠肌间神经丛中氮能神经元及NOS表达水平增加可能是急性力竭运动大鼠胃肠传输速率延迟的机制之一。
Zotero 插件