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[半胱胺对鹅胰腺分泌及酶活性的影响]

[Effect of cysteamine on the pancreatic secretion and enzymatic activity in geese].

作者信息

Ai Xiao-Jie, Han Zheng-Kang

机构信息

Animal Science Department, School of Agriculture & Biology, Shanghai Jiao Tong University, Shanghai 201101, China.

出版信息

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2002 Aug;18(3):297-300.

PMID:21180077
Abstract

AIM

To know the effect of cysteamine on the pancreatic secretion and enzyme activity in geese.

METHODS

Eight adult geese fitted chronic pancreatic and duodenal cannulas were used to evaluate the effect of cysteamine (CS) on the pancreatic secretion and enzyme activity. The experiment was consist of control and treated phase. CS was added in the diet at the dosage of 100 mg/kg bw on the first day of treated phase. The birds were free fed at daytime (8:00-20:00) and fasted at nighttime (20:00-8:00). The pancreatic juice samples were collected continuously for three days in each phase.

RESULTS

CS increased the average rate of pancreatic secretion by 240.16% (P < 0.01), in which that of daytime was elevated by 234.45% (P < 0.01), while that of nighttime elevated by 253.70% (P < 0.01). The secretion volume at daytime was more than that of night. CS increased trypsin activity by 49.05% (P < 0.01), whereas lipase and amylase activity was reduced by 25.44% (P < 0.01) and 21.95% (P < 0.01) separately. The one hour total activity of trypsin, lipase and amylase were elevated by 406.88% (P < 0.01), 153.58% (P < 0.01) and 166.59% (P < 0.01) respectively. Ratios of pancreatic secretion were different between day and night.

CONCLUSION

These results indicate that CS can affect the pancreatic juice secretion and pancreatic enzyme activity by depleting the somatostatin, so that benefits to improve the digestive foundation and supply more nutrition for quickly growing in geese.

摘要

目的

了解半胱胺对鹅胰腺分泌及酶活性的影响。

方法

选用8只安装了慢性胰管和十二指肠插管的成年鹅,以评估半胱胺(CS)对胰腺分泌及酶活性的影响。实验分为对照期和处理期。在处理期的第一天,以100 mg/kg体重的剂量将CS添加到饲料中。鹅在白天(8:00 - 20:00)自由采食,夜间(20:00 - 8:00)禁食。每个阶段连续三天收集胰液样本。

结果

CS使胰腺分泌的平均速率提高了240.16%(P < 0.01),其中白天提高了234.45%(P < 0.01),夜间提高了253.70%(P < 0.01)。白天的分泌量多于夜间。CS使胰蛋白酶活性提高了49.05%(P < 0.01),而脂肪酶和淀粉酶活性分别降低了25.44%(P < 0.01)和21.95%(P < 0.01)。胰蛋白酶、脂肪酶和淀粉酶的1小时总活性分别提高了406.88%(P < 0.01)、153.58%(P < 0.01)和166.59%(P < 0.01)。昼夜胰腺分泌比例不同。

结论

这些结果表明,CS可通过消耗生长抑素来影响胰液分泌和胰腺酶活性,从而有利于改善鹅的消化基础,为其快速生长提供更多营养。

相似文献

1
[Effect of cysteamine on the pancreatic secretion and enzymatic activity in geese].[半胱胺对鹅胰腺分泌及酶活性的影响]
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2002 Aug;18(3):297-300.
2
[Effects of cysteamine on the plasma levels of SS and some metabolic hormones in adult geese].
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2004 Feb;20(1):88-90.
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Studies on the exocrine function of healthy human pancreas: pancreatic juice and its certain components.
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Pflugers Arch. 1999 Mar;437(4):511-6. doi: 10.1007/s004240050811.
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Exogenous cysteamine increases basal pancreatic exocrine secretion in the rat.外源性半胱胺可增加大鼠胰腺基础外分泌。
J Korean Med Sci. 1999 Feb;14(1):52-6. doi: 10.3346/jkms.1999.14.1.52.
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Fiziol Zh SSSR Im I M Sechenova. 1972 Nov;58(11):1771-3.
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