鼻病毒 3C 蛋白酶的非共价抑制剂。
Non-covalent inhibitors of rhinovirus 3C protease.
机构信息
AstraZeneca, R&D Charnwood, Bakewell Road, Loughborough, Leicestershire LE11 5RH, UK.
出版信息
Bioorg Med Chem Lett. 2011 Jan 15;21(2):777-80. doi: 10.1016/j.bmcl.2010.11.110. Epub 2010 Nov 26.
PMID:21183345
Abstract
The first known non-covalent inhibitors of rhinovirus 3C protease (3CP) have been identified through fragment based screening and hit identification activities.
摘要
已通过基于片段的筛选和命中鉴定活动鉴定了首个已知的鼻病毒 3C 蛋白酶（3CP）非共价抑制剂。
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