Tran Diem Ngan, Blaszkiewicz Claire, Menuel Stéphane, Roucoux Alain, Philippot Karine, Hapiot Frédéric, Monflier Eric
Univ Lille Nord de France, F-59000 Lille, France.
Carbohydr Res. 2011 Feb 1;346(2):210-8. doi: 10.1016/j.carres.2010.11.024. Epub 2010 Nov 27.
A wide range of chiral mono- and ditopic cyclodextrin-based receptors have been synthesized by CuI-catalyzed azide-alkyne cycloaddition starting from mono-6-azido-β-cyclodextrin and chiral amino acids. Of interest, microwaves proved very efficient to access a wide range of ditopic β-cyclodextrin receptors with quantitative yields.
从单-6-叠氮基-β-环糊精和手性氨基酸出发，通过碘化亚铜催化的叠氮化物-炔烃环加成反应，已经合成了多种基于手性单齿和双齿环糊精的受体。有趣的是，事实证明微波能非常有效地以定量产率获得多种双齿β-环糊精受体。
