(-)-1-脱氧阿隆基来辛的快速实用合成法。
Rapid and practical synthesis of (-)-1-deoxyaltronojirimycin.
机构信息
Department of Chemistry, School of Science and Technology, Aalto University, P.O. Boc 16100 (Kemistintie 1), FI-00076, Aalto, Finland.
出版信息
Org Biomol Chem. 2011 Feb 21;9(4):1231-6. doi: 10.1039/c0ob00747a. Epub 2010 Dec 24.
PMID:21186396
Abstract
Herein a practical and scalable route to 1-deoxyaltronojirimycin is presented. The target is achieved in 9 steps and 43% yield featuring only two chromatographic purifications.
摘要
本文提出了一种实用且可规模化的 1-去氧阿洛酮糖基精氨酸的合成路线。该目标经 9 步反应，以 43%的总收率实现，仅需两次色谱纯化。
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