Pudar Goran, Vlaski Ljiljana, Filipović Danka, Tanackov Ilija
Opsta bolnica Dr. Dorde Joanovic, Odeljenje za otorinolaringologiju, Zrenjanin.
Med Pregl. 2010 May-Jun;63(5-6):318-23. doi: 10.2298/mpns1006318p.
Problems of hearing disturbances in persons suffering from diabetes have been attracting great attention for many decades.
In this study we examined the auditory function of 50 patients suffering from diabetes mellitus type 1 of different duration by analyzing results of pure-tone audiometry and brainstem auditory evoked potentials. The obtained results of measuring were compared to 30 healthy subjects from the corresponding age and gender group. The group of diabetic patients was divided according to the disease duration (I group 0-5 years; II group 6-10 years, III group over 10 years).
A statistically significant increase of sensorineural hearing loss was found in the diabetics according to the duration of their disease (I group = 14.09%, II group = 21.39%, III group = 104.89%). The results of the brain stem auditory evoked potentials, the significance threshold being p = 0.05 between the controls and the diabetics at all levels of absolute latency of right and left sides, did not show significant differences in the mean values. In the case of interwave latencies, the diabetic patients were found to have a significant qualitative difference of intervals I-III and I-V on both ears in the sense of internal distribution of response. In cases of sensorineural hearing loss we found a significant connection with prolonged latencies of I wave on the right ear and of I and V waves on the left ear. In all probability, the cause of these results could be found in distinctive individuality of the organism reactions to the consequences of this disease (disturbance in the distal part of N. cochlearis).
The results of research have shown the existence of a significant sensorineural hearing loss in the patients with diabetes mellitus type 1 in accordance to the disease duration. We also found qualitative changes of brainstem auditory evoked potentials in the diabetic patients in comparison to the controls as well as significant quantitative changes in regard to the presence of sensorineural hearing loss of the patients.
几十年来，糖尿病患者的听力障碍问题一直备受关注。
在本研究中，我们通过分析纯音听力测定和脑干听觉诱发电位的结果，对50例不同病程的1型糖尿病患者的听觉功能进行了检查。将所得测量结果与来自相应年龄和性别组的30名健康受试者进行比较。糖尿病患者组根据病程进行划分（I组0 - 5年；II组6 - 10年，III组超过10年）。
根据病程，糖尿病患者的感音神经性听力损失有统计学意义的增加（I组 = 14.09%，II组 = 21.39%，III组 = 104.89%）。脑干听觉诱发电位的结果，在左右两侧绝对潜伏期的所有水平上，对照组与糖尿病患者之间的显著性阈值为p = 0.05，平均值未显示出显著差异。在波间潜伏期方面，从反应的内部分布来看，发现糖尿病患者双耳的I - III和I - V间期存在显著的质性差异。在感音神经性听力损失的情况下，我们发现与右耳I波潜伏期延长以及左耳I波和V波潜伏期延长有显著关联。这些结果很可能是由于机体对该疾病后果（蜗神经远端紊乱）反应的独特个体性所致。
研究结果表明，1型糖尿病患者存在与病程相关的显著感音神经性听力损失。我们还发现，与对照组相比，糖尿病患者的脑干听觉诱发电位存在质性变化，以及患者感音神经性听力损失方面的显著定量变化。
