Aleksandrova E A, Lepilin A V, Kazimirova N E, Shul'diakov A A
Stomatologiia (Mosk). 2010;89(4):25-7.
For the purpose to determine the clinic-pathogenetic efficacy of Cycloferon liniment in the combined therapy of parodontitis of patients with focal tuberculosis medical examination and treatment of 40 patients is carried out. It is established, that use of liniment Cycloferon in the combined treatment of patients with focal tuberculosis allows to accelerate process of normalization of lipid peroxidation parameters and antioxidant potential of blood, to decrease infection load (Herpes symplex virus I, Candida albicans, Staphylococcus aureus) in parodontal recess and evidence of local inflammation with reduction of activity of the tumours necrosis factor and interleukin 1beta, that provides acceleration of recuperation processes, lowering the frequency of parodontitis relapses.
为确定环孢菌素搽剂在局灶性结核病患者牙周炎综合治疗中的临床致病疗效，对40例患者进行了医学检查和治疗。结果表明，在局灶性结核病患者的联合治疗中使用环孢菌素搽剂可加速脂质过氧化参数和血液抗氧化潜能的正常化进程，降低牙周隐窝中的感染负荷（单纯疱疹病毒I、白色念珠菌、金黄色葡萄球菌）以及局部炎症证据，同时降低肿瘤坏死因子和白细胞介素1β的活性，这有助于加速康复进程，降低牙周炎复发频率。
