Dorko Erik, Pilipčinec Emil, Rimárová Kvetoslava, Kostovčíková Jana
Department of Public Health, Faculty of Medicine, Pavol Jozef Šafárik University, Košice, Slovak Republic.
Ann Agric Environ Med. 2010;17(2):323-5.
Q fever is a zoonosis caused by infection with Coxiella burnetii. Although the reservoir of C. burnetii consists of various species, the most common sources of human infection are farm animals, such as cattle, goats, and sheep. The agent is typically transmitted by the aerosol route, and in more than half of the cases primary infection is symptomless. Clinical outcomes of C. burnetii infection in domestic ruminants consist of abortion and stillbirths in sheep and goats, while in cattle it causes infertility and mastitis. A serological survey for C. burnetii was undertaken on a population of sheep. A total of 269 sheep serum samples were collected and tested for the detection of antibodies against C. burnetii phase I and II antigens using an enzyme-linked immunosorbent assay. The herd investigated was tested twice, i.e. in 2000 and 2009, to detect the changes in seroprevalence. In the first year of investigation, the prevalence of antibodies against C. burnetii phase II antigen was estimated at 37.22% and ten years later at 58.42%. Antibodies against phase I antigen were not detected in any examined serum samples. The difference in seroprevalence after ten years of observation was significant (p = 0.001).
Q热是一种由伯氏考克斯体感染引起的人畜共患病。尽管伯氏考克斯体的宿主包括多种物种，但人类感染的最常见来源是农场动物，如牛、山羊和绵羊。病原体通常通过气溶胶途径传播，并且在超过半数的病例中，初次感染是无症状的。家畜反刍动物感染伯氏考克斯体的临床后果包括绵羊和山羊的流产和死产，而在牛中则会导致不育和乳腺炎。对一群绵羊进行了伯氏考克斯体的血清学调查。总共收集了269份绵羊血清样本，并使用酶联免疫吸附测定法检测针对伯氏考克斯体I期和II期抗原的抗体。对所调查的畜群进行了两次检测，即在2000年和2009年，以检测血清阳性率的变化。在调查的第一年，针对伯氏考克斯体II期抗原的抗体阳性率估计为37.22%，十年后为58.42%。在所检测的任何血清样本中均未检测到针对I期抗原的抗体。经过十年观察后血清阳性率的差异具有统计学意义（p = 0.001）。
