University of California San Francisco, San Francisco, CA 94105, USA.
J Womens Health (Larchmt). 2011 Jan;20(1):91-8. doi: 10.1089/jwh.2010.2081. Epub 2010 Dec 29.
We examined whether the non-pneumatic anti-shock garment (NASG) ameliorates the effects of delays in transport to and treatment at hospitals for women with postpartum hemorrhage (PPH) and postabortion hemorrhage (PAH) and investigated the effects of NASG use on timing of delivery of interventions in-hospital.
Pre/post studies of the NASG were conducted at hospitals in Cairo (n = 349 women), Assuit (n = 274), Southern Nigeria (n = 57), and Northern Nigeria (n = 124). In post-hoc analyses, comparisons of delays were conducted using analysis of variance (ANOVA), and associations of delays with extreme adverse outcomes (EAO, mortality or severe morbidity) were examined using chi-square tests, odds ratios (ORs), and multivariate logistic regression.
Median minutes from hemorrhage start to study admission differed by site, ranging from 15 minutes in Cairo to 225 minutes in Northern Nigeria (p < 0.001). Median minutes from study admission to blood transfusion ranged from 30 minutes in Cairo to 209 minutes in Southern Nigeria (p < 0.001). Twenty percent of women with ≥60 minutes between hemorrhage start and study admission experienced an EAO without the NASG compared with only 6% with the NASG (χ(2) = 13.71, p < 0.001). In-hospital delays in receiving intravenous (IV) fluids and blood were more common in the NASG phase.
Women with PPH or PAH in Egypt and Nigeria often face delays in reaching emergency obstetrical care facilities and delays in receiving definitive therapies after arrival. Our results indicate that the NASG can reduce the impact of these delays. Stabilization does not replace treatment, however, and delays in fluid/blood administration with NASG use must be avoided.
我们研究了非充气式抗休克服(NASG)是否能改善产后出血(PPH)和流产后出血(PAH)妇女在送往医院和接受治疗方面的延迟影响,并调查了 NASG 使用对医院内干预措施实施时机的影响。
在开罗(n=349 名妇女)、阿西乌特(n=274 名)、尼日利亚南部(n=57 名)和尼日利亚北部(n=124 名)的医院进行了 NASG 的前后研究。在事后分析中,使用方差分析(ANOVA)比较了延迟情况,使用卡方检验、比值比(OR)和多变量逻辑回归检查了延迟与极端不良结局(死亡或严重并发症)之间的关联。
从出血开始到研究入院的中位数分钟数因地点而异,从开罗的 15 分钟到尼日利亚北部的 225 分钟(p<0.001)。从研究入院到输血的中位数分钟数从开罗的 30 分钟到尼日利亚南部的 209 分钟(p<0.001)。与使用 NASG 的妇女相比,没有使用 NASG 的妇女在出血开始和研究入院之间≥60 分钟的比例中经历极端不良结局的比例为 20%,而使用 NASG 的妇女比例为 6%(χ²=13.71,p<0.001)。在接受静脉(IV)液体和血液方面,NASG 阶段的院内延迟更为常见。
埃及和尼日利亚的 PPH 或 PAH 妇女经常面临到达紧急产科护理设施的延迟,以及到达后接受确定性治疗的延迟。我们的结果表明,NASG 可以减轻这些延迟的影响。稳定并不能替代治疗,因此必须避免在使用 NASG 时延迟液体/血液的输注。