Narbone M C, Ruello C, Oliva A, Baviera G, D'Amico D, Bramanti P, Di Perri R
1st Department of Neurology, University of Messina, Italy.
Funct Neurol. 1990 Jan-Mar;5(1):49-53.
Six epileptic women, showing a clear increase in seizure frequency in the perimenstrual period, were studied during three consecutive menstrual cycles. At each control seizure occurrence, EEG recordings, endocrine profile and antiepileptic drug plasma levels were evaluated. The only pathological finding was the progesterone deficiency with a relative hyperestrogenism during the late luteal phase. Our data agree with other reports suggesting that catamenial epilepsy may result from a sex hormone disregulation.
对6名在月经周期期间癫痫发作频率明显增加的癫痫女性患者，进行了连续三个月经周期的研究。在每次对照癫痫发作时，评估脑电图记录、内分泌情况和抗癫痫药物血浆水平。唯一的病理发现是黄体晚期孕酮缺乏伴相对雌激素过多。我们的数据与其他报告一致，表明经期癫痫可能是由性激素失调引起的。
