Université catholique de Louvain, Institute of Mechanics, Materials and Civil Engineering, Av. G. Lemaitre, 4, 1348 Louvain-la-Neuve, Belgium.
J Biomech. 2011 Mar 15;44(5):897-903. doi: 10.1016/j.jbiomech.2010.11.036. Epub 2010 Dec 31.
In the context of patient-specific cardiovascular applications, hemodynamics models (going from 3D to 0D) are often limited to a part of the arterial tree. This restriction implies the set up of artificial interfaces with the remaining parts of the cardiovascular system. In particular, the inlet boundary condition is crucial: it supplies the impulsion to the system and receives the reflected backward waves created by the distal network. Some aspects of this boundary condition need to be properly defined such as the treatment of backward waves (reflected or absorbed) and the value of the imposed hemodynamic wave (total or forward component). Most authors prescribe as inlet boundary condition (BC) the total measured variable (pressure, velocity or flow rate) in a reflective way. We show that with this type of inlet boundary condition, the model does not produce physiological waveforms. We suggest instead to prescribe only the forward component of the prescribed variable in an absorbing way. In this way, the computed reflected waves superpose with the prescribed forward waves to produce the total wave at the inlet. In this work, different inlet boundary conditions are implemented and compared for a 1D blood flow model. We test our boundary conditions on a truncated arterial model presented in the literature as well as on a patient-specific lower-limb model of a femoral bypass. We show that with this new boundary condition, a much better fitting is observed on the shape and intensity of the simulated pressure and velocity waves.
在特定于患者的心血管应用中,血液动力学模型(从 3D 到 0D)通常仅限于动脉树的一部分。这种限制意味着需要与心血管系统的其余部分建立人工接口。特别是,入口边界条件至关重要:它为系统提供动力,并接收由远端网络产生的反射回波。该边界条件的某些方面需要正确定义,例如回波(反射或吸收)的处理以及施加的血液动力学波的值(总波或前向分量)。大多数作者以反射方式规定入口边界条件(BC)为总测量变量(压力、速度或流量)。我们表明,使用这种类型的入口边界条件,模型不会产生生理波形。相反,我们建议以吸收方式仅规定规定变量的前向分量。通过这种方式,计算出的反射波与规定的前向波叠加,在入口处产生总波。在这项工作中,为一维血流模型实现并比较了不同的入口边界条件。我们在文献中提出的截断动脉模型以及患者特定的股动脉旁路下肢模型上测试了我们的边界条件。我们表明,使用这种新边界条件,模拟压力和速度波的形状和强度可以得到更好的拟合。