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[不同无菌培养的溶组织内阿米巴菌株对替代补体途径的活性]

[Activity of the alternative complement pathway by various axenic strains of Entamoeba histolytica].

作者信息

Capin N R, Capin R, Zamacona G, Ortiz-Ortiz L

出版信息

Arch Invest Med (Mex). 1978;9 Suppl 1:291-6.

PMID:211963
Abstract

The activation of the alternative pathway of complement by axenic cultures of E. histolytica is reported. The activation is carried out in different proportions by several axenic strains, i.e., HK9:NIH, HM1:IMSS, HM2:IMSS and HM3:IMSS; the end result consists of a destruction of the parasite as well as consumption of the serum complement. The participation of the alternative pathway was studied in the presence of EGTA and Mg++, zymosan, heat-inactivation at 50 degree C for 20 min and immunoelectrophoretic studied with anti-factor B.

摘要

据报道,溶组织内阿米巴的无菌培养物可激活补体替代途径。几种无菌菌株,即HK9:NIH、HM1:IMSS、HM2:IMSS和HM3:IMSS,以不同比例进行激活;最终结果是寄生虫被破坏以及血清补体被消耗。在存在乙二醇双四乙酸(EGTA)和镁离子(Mg++)、酵母聚糖、50℃热灭活20分钟以及用抗B因子进行免疫电泳研究的情况下,对替代途径的参与情况进行了研究。

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