韩国患多浆膜炎猪源猪链球菌的荚膜血清型及毒力标志物分布情况
Distribution of capsular serotypes and virulence markers of Streptococcus suis isolated from pigs with polyserositis in Korea.
作者信息
Kim Duyeol, Han Kiwon, Oh Yeonsu, Kim Chung Hyun, Kang Ikjae, Lee Jeehoon, Gottschalk Marcelo, Chae Chanhee
机构信息
Department of Veterinary Pathology, Seoul National University, Shillim-dong, Gwanak-gu, Republic of Korea.
出版信息
Can J Vet Res. 2010 Oct;74(4):314-6.
Abstract
The objective of this study was to determine the capsular serotypes and potential virulence factors of Streptococcus suis isolated from pigs with polyserositis. Among the 24 isolates evaluated, serotype 3 [7 (29%) of the isolates] and serotype 4 [5 (21%)] were the most common. The isolates were also studied for the presence of the genes mrp, epf, and sly, which encode muramidase-released protein (MRP), extracellular factor (EF), and suilysin (SLY), respectively. Of the 24 isolates, 8 carried mrp: 4 of serotype 3, 2 of serotype 2, and 2 of serotype 4. One mrp(+) isolate (serotype 2) also carried the epf gene. All 24 isolates carried the sly gene. The serotype and genotype distribution greatly differed from that reported for isolates from pigs with other clinical manifestations of S. suis infection in other countries.
摘要
本研究的目的是确定从患有多浆膜炎的猪中分离出的猪链球菌的荚膜血清型和潜在毒力因子。在所评估的24株分离株中，3型[7株（29%）分离株]和4型[5株（21%）]最为常见。还对分离株进行了mrp、epf和sly基因的检测，这三个基因分别编码溶菌酶释放蛋白（MRP）、细胞外因子（EF）和溶血素（SLY）。在24株分离株中，8株携带mrp基因：3型4株、2型2株、4型2株。一株携带mrp基因的分离株（2型）也携带epf基因。所有24株分离株均携带sly基因。血清型和基因型分布与其他国家报道的患有猪链球菌感染其他临床表现的猪的分离株有很大差异。
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