University of Adelaide Discipline of Medicine, Royal Adelaide Hospital, South Australia, Australia.
J Gastroenterol Hepatol. 2011 Jan;26 Suppl 1:46-57. doi: 10.1111/j.1440-1746.2010.06573.x.
Diabetic gastroparesis was once thought to be rare, associated with a poor prognosis, and to affect only patients with type 1 diabetes and irreversible autonomic neuropathy. A landmark study conducted by Horowitz et al. and published in JGH in 1986 paved the way for further studies to examine the pathophysiology, natural history and prognosis of diabetic gastroparesis, as well as its optimal management. This review summarizes the developments in knowledge gained over the last ∼25 years that have led to understanding about normal and disordered gastric emptying in diabetes, with a particular emphasis on the inter-relationship between the rate of gastric emptying and the regulation of blood glucose.
糖尿病性胃轻瘫曾被认为较为罕见，预后不良，且仅影响 1 型糖尿病和不可逆转自主神经病变的患者。1986 年，由 Horowitz 等人进行的一项具有里程碑意义的研究发表在《JGastroenterol》上，为进一步研究糖尿病性胃轻瘫的病理生理学、自然史和预后及其最佳治疗铺平了道路。这篇综述总结了过去 25 年左右的研究进展，这些进展使我们对糖尿病时正常和紊乱的胃排空有了更多的了解，特别强调了胃排空率与血糖调节之间的相互关系。
