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6'-氨基-3'-甲基-2-氧代-1'-苯基-1',3a',4',7a'-四氢螺[1H-吲哚-3(2H),4'-吡喃并[2,3-d]吡唑]-5'-甲腈

6'-Amino-3'-methyl-2-oxo-1'-phenyl-1',3a',4',7a'-tetra-hydrospiro-[1H-indole-3(2H),4'-pyrano[2,3-d]pyrazole]-5'-carbonitrile.

作者信息

Etti S, Shanthi G, Shanmugam G, Perumal P T

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2007 Dec 21;64(Pt 1):o341. doi: 10.1107/S1600536807064926.

DOI:10.1107/S1600536807064926
PMID:21200903
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2915382/
Abstract

In the crystal structure of the title compound, C(21)H(15)N(5)O(2), the planar indolone unit and the pyran ring are almost perpendicular to each other [dihedral angle = 89.41 (2)°], and the pyrazole and phenyl rings are oriented at an angle of 25.74 (1)°. The mol-ecular packing is stabilized by inter- and intra-molecular C-H⋯O, N-H⋯O and C-H⋯π hydrogen bonds.

摘要

在标题化合物C(21)H(15)N(5)O(2)的晶体结构中，平面吲哚酮单元和吡喃环几乎相互垂直[二面角 = 89.41 (2)°]，吡唑环和苯环的取向角度为25.74 (1)°。分子堆积通过分子间和分子内的C—H⋯O、N—H⋯O和C—H⋯π氢键得以稳定。

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6'-Amino-3'-methyl-2-oxo-1'-phenyl-1',3a',4',7a'-tetra-hydrospiro-[1H-indole-3(2H),4'-pyrano[2,3-d]pyrazole]-5'-carbonitrile.6'-氨基-3'-甲基-2-氧代-1'-苯基-1',3a',4',7a'-四氢螺[1H-吲哚-3(2H),4'-吡喃并[2,3-d]吡唑]-5'-甲腈
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本文引用的文献

1
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Farmaco. 2002 Sep;57(9):715-22. doi: 10.1016/s0014-827x(02)01263-6.
2
Pteropodine and isopteropodine positively modulate the function of rat muscarinic M(1) and 5-HT(2) receptors expressed in Xenopus oocyte.蝙蝠葛碱和异蝙蝠葛碱正向调节非洲爪蟾卵母细胞中表达的大鼠毒蕈碱M(1)和5-羟色胺(2)受体的功能。
Eur J Pharmacol. 2002 May 24;444(1-2):39-45. doi: 10.1016/s0014-2999(02)01608-4.
3
Tryprostatin A, a specific and novel inhibitor of microtubule assembly.
曲前列他汀A，一种特异性新型微管组装抑制剂。
Biochem J. 1998 Aug 1;333 ( Pt 3)(Pt 3):543-8. doi: 10.1042/bj3330543.