Gowda B Thimme, Foro Sabine, Fuess Hartmut
Acta Crystallogr Sect E Struct Rep Online. 2008 Jan 9;64(Pt 2):o381. doi: 10.1107/S1600536807068808.
The conformation of the N-H bond in the structure of the title compound (3CPA), C(8)H(8)ClNO, is anti to the meta-chloro substituent, in contrast to the syn conformation observed for the ortho-chloro substituent in N-(2-chloro-phen-yl)acetamide, syn to both the ortho and meta chloro substituents in N-(2,3-dichloro-phen-yl)acetamide, and syn to the ortho chloro substituent in N-(2,4-dichloro-phen-yl)acetamide. There are two mol-ecules, linked by an N-H⋯O hydrogen bond, in the asymmetric unit of 3CPA. The bond parameters in 3CPA are similar to those of other acetanilides and the mol-ecules are packed into chains through inter-molecular N-H⋯O hydrogen bonds.
标题化合物（3CPA），即C(8)H(8)ClNO的结构中，N - H键的构象与间位氯取代基呈反式，这与N-(2 - 氯苯基)乙酰胺中邻位氯取代基的顺式构象、N-(2,3 - 二氯苯基)乙酰胺中邻位和间位氯取代基均为顺式构象以及N-(2,4 - 二氯苯基)乙酰胺中邻位氯取代基为顺式构象不同。在3CPA的不对称单元中有两个通过N - H⋯O氢键相连的分子。3CPA中的键参数与其他乙酰苯胺类化合物的相似，分子通过分子间N - H⋯O氢键堆积成链状。
