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双(1,2,3,4-四氢喹啉-6-基)甲烷

Bis(1,2,3,4-tetra-hydro-quinolin-6-yl)methane.

作者信息

Shen Li, Liu Qi, Shen Hai-Jun

机构信息

Medical College, Yangzhou University, Yangzhou 225001, Jiangsu Province, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Aug 13;64(Pt 9):o1747. doi: 10.1107/S1600536808025464.

DOI:10.1107/S1600536808025464
PMID:21201729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2960691/
Abstract

The asymmetric unit of the title compound, C(19)H(22)N(2), contains one half-mol-ecule. The 1,2,3,4-tetra-hydro-quinoline units are linked by a methyl-ene bridge, which lies on a twofold rotation axis. The non-aromatic ring adopts a flattened-boat conformation. The dihedral angle between the two symmetry-related benzene rings is 64.03 (7)°.

摘要

标题化合物C(19)H(22)N(2)的不对称单元包含半个分子。1,2,3,4-四氢喹啉单元通过一个亚甲基桥相连,该亚甲基桥位于一个二重旋转轴上。非芳香环呈扁平船式构象。两个对称相关的苯环之间的二面角为64.03 (7)°。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5722/2960691/c58226f5634d/e-64-o1747-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5722/2960691/c58226f5634d/e-64-o1747-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5722/2960691/c58226f5634d/e-64-o1747-fig1.jpg

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本文引用的文献

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2
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Eur J Med Chem. 2008 Sep;43(9):1828-36. doi: 10.1016/j.ejmech.2007.11.026. Epub 2007 Dec 8.
3
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
4
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Bioorg Med Chem. 2007 Jun 15;15(12):4212-9. doi: 10.1016/j.bmc.2007.03.060. Epub 2007 Mar 24.
5
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Bioorg Med Chem. 2007 Jun 1;15(11):3703-10. doi: 10.1016/j.bmc.2007.03.045. Epub 2007 Mar 18.