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3-[(R)-3,3-二氯-2-羟基丙基]-8-羟基-6-甲氧基-1H-异苯并呋喃-1-酮

3-[(R)-3,3-Dichloro-2-hydroxy-prop-yl]-8-hydr-oxy-6-meth-oxy-1H-isochromen-1-one.

作者信息

Huang Hua-Rong, Fang Yan-Xiong, Du Zhi-Yun, Zhang Kun, Lin Yong-Cheng

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Aug 20;64(Pt 9):o1801. doi: 10.1107/S1600536808026391.

DOI:10.1107/S1600536808026391
PMID:21201780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2960720/
Abstract

The title compound, C(13)H(12)Cl(2)O(5), is an isocoumarin compound which has been isolated from the ethyl acetate extract of the fermentation broth of actinomycete Streptomyces sp. (V(4)) from the South China Sea. There are intra- and inter-molecular hydrogen bonds and halogen bonds [Cl⋯Cl = 3.434 (2) Å; C-Cl⋯Cl = 121.6°]. The intermolecular O-H⋯O hydrogen bonds link mol-ecules into chains along the b axis.

摘要

标题化合物C₁₃H₁₂Cl₂O₅是一种异香豆素化合物，从中国南海放线菌链霉菌属（V₄）发酵液的乙酸乙酯提取物中分离得到。存在分子内和分子间氢键以及卤键[Cl⋯Cl = 3.434 (2) Å；C-Cl⋯Cl = 121.6°]。分子间O-H⋯O氢键将分子沿b轴连接成链。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ea/2960720/bbb03b63aea9/e-64-o1801-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ea/2960720/6f4d1b5e6f6d/e-64-o1801-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ea/2960720/78bb9a62ed66/e-64-o1801-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ea/2960720/bbb03b63aea9/e-64-o1801-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ea/2960720/6f4d1b5e6f6d/e-64-o1801-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ea/2960720/78bb9a62ed66/e-64-o1801-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ea/2960720/bbb03b63aea9/e-64-o1801-fig3.jpg

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本文引用的文献

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A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
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Dichlorodiaportin, diaportinol, and diaportinic acid: three novel isocoumarins from penicillium nalgiovense.二氯二aportin、aportinol和aportinic酸：来自纳氏青霉的三种新型异香豆素。
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