Flores Emily K, Henry Robin, Stewart David W
Department of Pharmacy Practice, Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN 37614, USA.
South Med J. 2011 Feb;104(2):143-6. doi: 10.1097/SMJ.0b013e318200c1ec.
Falls are caused by many factors in older patients. Medications have been shown to be a risk factor for falls, and studies have shown that patients taking more than five total medications may have a two-fold increased risk of impaired balance. A more recent model suggests only medications with sedating and anticholinergic properties contribute significantly to physical impairment. The authors of this paper helped to develop a multidisciplinary clinic to evaluate the risk of falls in at-risk patients. We present the case of a woman on multiple medications that increased her risk of falling. Of note, this patient was taking a total of 14 prescription medications, seven of which were considered sedating. Based on a comprehensive medication evaluation, six specific changes were recommended to improve this patient's medication regimen and reduce her risk of falling.
跌倒在老年患者中是由多种因素引起的。药物已被证明是跌倒的一个风险因素，研究表明，服用总共五种以上药物的患者平衡受损风险可能会增加两倍。最近的一个模型表明，只有具有镇静和抗胆碱能特性的药物才会对身体损伤有显著影响。本文的作者协助建立了一个多学科诊所，以评估高危患者的跌倒风险。我们介绍了一名服用多种增加跌倒风险药物的女性病例。值得注意的是，该患者总共服用了14种处方药，其中7种被认为具有镇静作用。基于全面的药物评估，建议进行六项具体调整，以改善该患者的用药方案并降低其跌倒风险。
