S. CHAUDHURY, M.D. Ph.D, Head, Department of Psychiatry, 151 Base Hospital, Guwahati.
Indian J Psychiatry. 2002 Apr;44(2):144-9.
In 100 consecutive male inpatients with alcohol dependence and an equal number of age, sex, occupation and regional background matched controls, the value ofgamma-glutamyl transpeptidase (GGT), serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), mean corpuscular volume (MCV) and serum triglycerides were statistically significantly raised among alcoholics on admission as compared to controls. After five weeks of enforced abstinence in hospital the values of GGT, SGOT and SGPT showed significant reduction among alcohol consumption, these objective laboratory tests can be used to support the clinical diagnosis of alcohol dependence. Electrocardiographic abnormalities viz. Sinus tachycardia, intraventricular conduction defects, T wave abnormalities and QTC prolongation occurred significantly more frequently in alcohol dependence patients as compared to normal controls.
在 100 例连续的酒精依赖男性住院患者和数量相等的年龄、性别、职业和地区背景匹配的对照组中，与对照组相比，入院时γ-谷氨酰转肽酶（GGT）、血清谷氨酸草酰乙酸转氨酶（SGOT）、血清谷氨酸丙酮酸转氨酶（SGPT）、平均红细胞体积（MCV）和血清甘油三酯的数值在酒精依赖者中统计学上显著升高。在医院强制戒酒后五周，GGT、SGOT 和 SGPT 的值显著下降，这些客观的实验室测试可用于支持酒精依赖的临床诊断。与正常对照组相比，心电图异常如窦性心动过速、室内传导障碍、T 波异常和 QTC 延长在酒精依赖患者中发生的频率显著更高。
