NILAMADHAB KAR, MD, DPM, DNB, Consultant Psychiatrist, Wolverhampton Primary Care NHS Trust, Corner House Resource Centre, 300, Dunstall Road, Wolverhampton, WV6 0NZ, United Kingdom.
Indian J Psychiatry. 2003 Jul;45(3):174-7.
The factors influencing the short-term outcome of alcohol dependence patients psychiatric set up were studied prospectively in an Indian population. Consecutive 60 patients with alcohol dependence syndrome according to the ICD 10 criteria, were studied. Positive outcome was noted in 55%, negative in 35%; and 10% were lost to follow up at the end of one year. There was no difference between the groups on educational level, marital status, economic status, religion, social support, associated physical or psychiatric diagnoses, type of treatment for deaddiction, age of regular drinking, days of previous abstinence and inpatient treatment days. However the negative outcome group were younger, and their average age for problem drinking was significantly less than the other group. They achieved many mile-stones of drinking career like onset of day drinking, development of dependence, diagnosis of dependence earlier. The negative outcome group also had higher psychosocial problem index, family history of alcoholism, more follow-up days using the mental health services. They did not come for follow up as quickly as the abstinent group after initiation of pathological drinking.The study suggested many clearly identifiable variables, which may distinguish prospectively patients with probable positive and negative outcome one year after the alcohol deaddiction treatment.
本研究旨在前瞻性地探讨影响印度酒精依赖患者短期转归的因素。连续入组 60 例符合 ICD-10 酒精依赖综合征诊断标准的患者，1 年后随访发现，55%的患者结局良好，35%的患者结局不佳，10%的患者失访。两组患者在教育程度、婚姻状况、经济状况、宗教信仰、社会支持、躯体或精神共病、脱瘾治疗方式、饮酒起始年龄、既往戒断天数、住院天数等方面均无差异。然而，结局不佳组患者更年轻，且其开始出现问题性饮酒的年龄明显小于其他组。他们在饮酒生涯中达到了许多里程碑，如开始日间饮酒、出现依赖、更早被诊断为依赖。此外，结局不佳组患者的心理社会问题指数更高，有酒精滥用家族史，使用精神卫生服务的随访天数更多。与完全戒酒组相比，这些患者在开始出现病理性饮酒后，并不像后者那样及时前来随访。本研究提示，在接受酒精脱瘾治疗 1 年后，存在许多可明确识别的变量，这些变量可能有助于前瞻性地区分预后良好和预后不佳的患者。
