McEwan G T, Schousboe B, Skadhauge E
Dept. of Physiological Sciences, Medical School, Univ. of Newcastle upon Tyne, England, U.K.
Zentralbl Veterinarmed A. 1990 Jul;37(6):439-44. doi: 10.1111/j.1439-0442.1990.tb00926.x.
The mucosal surface pH of pig jejunum was measured in vivo. When the pH in the bulk phase of the perfusing buffer solution was 7.10, the pH at the mucosa (as measured by a miniaturised glass pH electrode) was 6.19 +/- 0.04 (n = 19). This relatively acidic mucosal surface pH is not an anoxic artefact since anoxia resulted in a significant alkalinisation of the mucosa. This finding, that the pig, like man and the rat, has a jejunal "acid microclimate" has important implications for weak electrolyte absorption from the upper small intestine of this species as well as for any other pH dependent brush border process.
在体内测量了猪空肠的黏膜表面pH值。当灌注缓冲溶液的主体相pH值为7.10时，黏膜处的pH值（通过微型玻璃pH电极测量）为6.19±0.04（n = 19）。这种相对酸性的黏膜表面pH值并非缺氧假象，因为缺氧会导致黏膜显著碱化。这一发现，即猪与人和大鼠一样，存在空肠“酸性微环境”，对于该物种上小肠中弱电解质的吸收以及任何其他依赖pH值的刷状缘过程都具有重要意义。
