Department of Obstetrics and Gynecology, the University of Sydney at Westmead Hospital, New South Wales, Australia.
Ultrasound Med Biol. 2011 Feb;37(2):184-8. doi: 10.1016/j.ultrasmedbio.2010.10.027. Epub 2011 Jan 5.
The isovolumetric contraction time (ICT) is known to be an index of cardiac contractility. In this study, we examined the relationship between the fetal ICT and fetal heart rate (FHR) and evaluated the usefulness of ICT in the assessment of fetal cardiac contractility in cases with fetal tachyarrhythmia. Seven cases with fetal tachyarrhythmia between 32 and 40 weeks' gestation were included in this study. The fetal ICT was measured using a continuous Doppler device and digital filters. The relationship between the fetal ICT and FHR was analyzed using the Spearman's rank correlation test in each fetus. Based on the FHR and ultrasound findings of hydrops at the measurement of ICT, the obtained data were divided into three groups: normal, tachyarrhythmia only and hydrops. The clinical usefulness of ICT was assessed using the random effect model. In 7 fetuses, a total of 60 data points were obtained. A significant correlation between fetal ICT and FHR was not noted in each fetus. The ICT of the hydrops group was significantly prolonged compared with those of the normal and tachyarrhythmia-only groups (p < 0.01). An association between the fetal ICT and FHR is not noted and the fetal ICT might have some utility to detect impaired fetal cardiac contractility even in fetuses with tachyarrhythmia.
等容收缩时间（ICT）是众所周知的心脏收缩力的指标。在这项研究中，我们检查了胎儿 ICT 和胎儿心率（FHR）之间的关系，并评估了 ICT 在评估胎儿心动过速情况下胎儿心脏收缩功能中的作用。本研究纳入了 7 例 32 至 40 孕周胎儿心动过速患者。使用连续多普勒设备和数字滤波器测量胎儿 ICT。在每个胎儿中，使用 Spearman 秩相关检验分析胎儿 ICT 和 FHR 之间的关系。根据 ICT 测量时 FHR 和胎儿水肿的超声表现，将获得的数据分为三组：正常、心动过速仅和水肿。使用随机效应模型评估 ICT 的临床实用性。在 7 例胎儿中，共获得 60 个数据点。在每个胎儿中，均未发现胎儿 ICT 和 FHR 之间存在显著相关性。水肿组的 ICT 明显长于正常组和心动过速组（p<0.01）。胎儿 ICT 和 FHR 之间没有关联，即使在患有心动过速的胎儿中，胎儿 ICT 也可能具有检测胎儿心脏收缩功能障碍的一些作用。
