Department of Clinical Medicine, Section of Experimental and Clinical Pharmacology, University of Insubria, Varese, Italy.
Scand J Med Sci Sports. 2011 Dec;21(6):e247-59. doi: 10.1111/j.1600-0838.2010.01263.x. Epub 2011 Jan 7.
Internet websites offering androgenic anabolic steroids (AAS) were identified and available products were examined. Keywords for the website search were: "anabolic steroids," "anabolic steroids buy," "anabolic steroid purchase." The first 10 websites offering AAS in the first 10 pages of results were considered. At least two AAS-containing products per website were selected. Thirty AAS-selling websites were identified, mainly located in the United States (46.7%) and Europe (30%). Most websites sold other anabolic/ergogenic products (clenbuterol, 76.7%; GH/IGF, 60.0%; thyroid hormones, 46.7%; erythropoietin, 30.0%; insulin, 20.0%) or products for AAS-related adverse effects (mainly: estrogen antagonists, 63.3%; products for erectile dysfunction, 56.7%; 5α-reductase inhibitors, 33.3%; anti-acne products, 33.3%). AAS were sold as medicines (69.6%) or as dietary supplements (30.4%). AAS in medicines were mainly: nandronole (20.4%), methandrostenolone (18.4%), and testosterone (12.2%). Dietary supplements contained mainly DHEA and included several fake compounds. Manufacturers were declared for 97.9% of medicines and 66.7% of dietary supplements; however, several manufacturers were not found on the Internet. Described benefits were usually few adverse effects and no estrogenicity. Toxicity was seldom reported and presented as mild. Recommended doses were two-fourfold higher than current medical recommendations. In conclusion, misleading information and deceiving practices were common findings on AAS-selling websites, indicating their deleterious potential for public health.
互联网网站提供雄激素同化类固醇(AAS)被确定,并审查了可用的产品。网站搜索的关键词是:“合成代谢类固醇”,“合成代谢类固醇购买”,“合成代谢类固醇购买”。考虑了前 10 个提供 AAS 的网站,这些网站在前 10 页的搜索结果中。每个网站至少选择两种含有 AAS 的产品。确定了 30 个销售 AAS 的网站,主要位于美国(46.7%)和欧洲(30%)。大多数网站销售其他合成代谢/增强性功能的产品(克伦特罗,76.7%;生长激素/胰岛素样生长因子,60.0%;甲状腺激素,46.7%;促红细胞生成素,30.0%;胰岛素,20.0%)或与 AAS 相关的不良反应的产品(主要是:雌激素拮抗剂,63.3%;治疗勃起功能障碍的产品,56.7%;5α-还原酶抑制剂,33.3%;治疗痤疮的产品,33.3%)。AAS 被作为药品(69.6%)或膳食补充剂(30.4%)出售。药品中的 AAS 主要是:诺龙(20.4%),美雄酮(18.4%)和睾酮(12.2%)。膳食补充剂主要含有脱氢表雄酮,并包含几种假冒化合物。药品制造商的声明占 97.9%,膳食补充剂制造商的声明占 66.7%;然而,有几个制造商在互联网上找不到。描述的好处通常是很少的副作用和没有雌激素活性。毒性很少被报道,且被描述为轻微的。推荐剂量是目前医学建议的两倍到四倍。总之,在销售 AAS 的网站上,常见的是误导性信息和欺骗性做法,这表明它们对公共健康有潜在的危害。