Division of Vascular Surgery and Endovascular Therapy, University of Florida, Gainesville, Fla., USA.
J Vasc Surg. 2011 Apr;53(4):895-904; discussion 904-5. doi: 10.1016/j.jvs.2010.10.068. Epub 2011 Jan 6.
OBJECTIVE: To compare early outcomes of endovascular repair of juxtarenal and suprarenal aneurysms using the chimney technique with open repair in anatomically-matched patients. METHODS: Between January 2008 and December 2009, 21 patients underwent endovascular repair of juxtarenal and suprarenal aortic aneurysms with chimney stenting (Ch-EVAR) of 1 or 2 renal and/or superior mesenteric artery (SMA) vessels. These were compared with 21 anatomically-matched patients that underwent open repair (OR) during the same time period. Primary end points were 30-day mortality, chimney stent patency, and type Ia endoleak. Secondary end points included early complications, renal function, blood loss, and length of stay (LOS). RESULTS: Despite a higher proportion of women, oxygen-dependent pulmonary disease and lower baseline renal function, 30-day mortality was identical with one death (4.8%) in each group. Blood loss and total LOS were significantly less for Ch-EVAR. Six patients (29%) in the chimney group had acute kidney injury (AKI) compared with the open group, in which there were one (4.8%) AKI and four (19%) acute renal failures, of which two (9.5%) required chronic hemodialysis. Renal function at 12 months demonstrated similar declines in the overall estimated glomerular filtration rate (eGFR) in the Ch-EVAR and OR groups (11.1 ± 19.6 vs 10.4 ± 25.2, P = NS, respectively). There was one asymptomatic SMA stent occlusion at 6 months and partial compression of a second SMA stent which underwent repeat balloon angioplasty. Primary patency at 6 and 12 months was 94% and 84%, respectively. There was one type Ia endoleak noted at 30 days which resolved by 6 months. CONCLUSIONS: Ch-EVAR may extend the anatomical eligibility of endovascular aneurysm repair using conventional devices. It appears to have similar mortality to open repair with less morbidity. Long-term durability and stent patency remain to be determined.
目的:比较腔内修复肾周和肾上动脉瘤时采用烟囱技术与开放修复在解剖匹配患者中的早期结果。
方法:2008 年 1 月至 2009 年 12 月,21 例患者接受腔内修复肾周和肾上主动脉瘤的治疗,采用烟囱支架(Ch-EVAR)治疗 1 或 2 个肾和/或肠系膜上动脉(SMA)血管。这些患者与同期接受开放修复(OR)的 21 例解剖匹配患者进行比较。主要终点是 30 天死亡率、烟囱支架通畅性和 I 型内漏。次要终点包括早期并发症、肾功能、出血量和住院时间(LOS)。
结果:尽管女性比例较高、氧依赖型肺病和较低的基线肾功能,但两组 30 天死亡率相同,各有 1 例(4.8%)死亡。Ch-EVAR 的出血量和总 LOS 明显减少。Chimney 组有 6 例(29%)患者发生急性肾损伤(AKI),而开放组有 1 例(4.8%)AKI 和 4 例(19%)急性肾衰竭,其中 2 例(9.5%)需要慢性血液透析。12 个月时,Ch-EVAR 和 OR 组的总体估计肾小球滤过率(eGFR)均有相似程度的下降(分别为 11.1±19.6%和 10.4±25.2%,P=NS)。6 个月时出现 1 例无症状 SMA 支架闭塞,对第二例 SMA 支架进行重复球囊血管成形术。6 个月和 12 个月时的主要通畅率分别为 94%和 84%。30 天时发现 1 例 I 型内漏,6 个月时得到解决。
结论:Ch-EVAR 可能扩大使用传统器械进行腔内动脉瘤修复的解剖适应证。它的死亡率似乎与开放修复相似,发病率较低。长期耐久性和支架通畅性仍有待确定。
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