Bender J W, Davitt M K, Jose P
Biol Neonate. 1978;34(1-2):19-23. doi: 10.1159/000241100.
Cord blood angiotensin-I-converting enzyme (ACE) activity was examined in 21 term and 21 premature infants. Values were significantly higher in premature infants than in term infants. Cord blood ACE activity was found to have a significant negative correlation with birth weight and gestational age. ACE activity measured from peripheral blood during the first 24 h of life was higher in premature than term infants but similar to levels in maternal and adult controls. It was not possible to predict those premature infants who would develop respiratory distress syndrome on the basis of cord blood ACE activity. However, ACE may serve as a marker for maturation of the pulmonary vascular endothelial cell.
对21名足月儿和21名早产儿的脐血血管紧张素转换酶（ACE）活性进行了检测。早产儿的ACE活性值显著高于足月儿。发现脐血ACE活性与出生体重和胎龄呈显著负相关。出生后24小时内从外周血测得的ACE活性，早产儿高于足月儿，但与母亲和成人对照组的水平相似。根据脐血ACE活性无法预测哪些早产儿会发生呼吸窘迫综合征。然而，ACE可能作为肺血管内皮细胞成熟的一个标志物。
