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加拿大第一民族人群中的肥胖及肥胖相关合并症

Obesity and obesity-related comorbidities in a Canadian First Nation population.

作者信息

Bruce S G, Riediger N D, Zacharias J M, Young T K

机构信息

University of Manitoba, Winnipeg, Manitoba, Canada.

出版信息

Chronic Dis Can. 2010 Dec;31(1):27-32.

Abstract

INTRODUCTION

Rates of obesity are higher among Canada's Aboriginal First Nations populations than among non-First Nations populations. We studied obesity and obesity-related illness in a Manitoba First Nation community.

METHODS

We conducted a screening study of diabetes and diabetes complications in 2003, from which we drew a representative sample of Manitoba First Nation adults (N = 483). We assessed chronic disease and chronic disease risk factors.

RESULTS

Prevalence of obesity and associated comorbidities was higher among women than men. By using multivariate analysis, we found that factors significantly associated with obesity among women were diastolic blood pressure, insulin resistance, and employment status. Among men, factors were age, apolipoprotein A1 level, apolipoprotein B level, and insulin resistance. Seventy-five percent of study participants had at least 1 of the following conditions: obesity, dyslipidemia, hypertension, or diabetes. Comorbidity was high even among the youngest age groups; 22% of men and 43% of women aged 18 to 29 had 2 or more chronic conditions. Twenty-two percent of participants had undiagnosed hypertension. Participants with undiagnosed hypertension had significantly more chronic conditions and were more likely to have microalbuminuria than were those without hypertension. The number of chronic conditions was not significantly different for participants with newly diagnosed hypertension than for those with previously diagnosed hypertension.

CONCLUSION

The prevalence of obesity and other chronic conditions in the study community is high, especially considering the number of young people. Community-based interventions are being undertaken to reduce the excessive rate of illness.

摘要

引言

加拿大原住民第一民族人群的肥胖率高于非第一民族人群。我们对曼尼托巴省一个第一民族社区的肥胖及肥胖相关疾病进行了研究。

方法

2003年,我们针对糖尿病及糖尿病并发症开展了一项筛查研究,从中抽取了曼尼托巴省第一民族成年人的代表性样本(N = 483)。我们评估了慢性病及慢性病风险因素。

结果

肥胖及相关合并症的患病率女性高于男性。通过多变量分析,我们发现女性中与肥胖显著相关的因素为舒张压、胰岛素抵抗及就业状况。男性中,相关因素为年龄、载脂蛋白A1水平、载脂蛋白B水平及胰岛素抵抗。75%的研究参与者至少患有以下一种疾病:肥胖、血脂异常、高血压或糖尿病。即使在最年轻的年龄组中,合并症的发生率也很高;18至29岁的男性中有22%、女性中有43%患有两种或更多种慢性病。22%的参与者患有未确诊的高血压。与未患高血压的参与者相比,患有未确诊高血压的参与者患有更多慢性病,且更有可能出现微量白蛋白尿。新诊断为高血压的参与者与先前诊断为高血压的参与者的慢性病数量无显著差异。

结论

研究社区中肥胖及其他慢性病的患病率很高,尤其是考虑到年轻人的数量。目前正在开展基于社区的干预措施以降低过高的发病率。

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