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羊膜角膜缘干细胞移植治疗儿童单眼化学伤

Limbal stem cell transplantation with amniotic membrane for the treatment of uniocular chemical burn in children.

作者信息

Canturk Silay, Akova Yonca, Oner Veysi

机构信息

Baskent University School of Medicine, Department of Ophthalmology, Ankara, Turkey.

出版信息

J Pediatr Ophthalmol Strabismus. 2010 May 21;47 Online:e1-5. doi: 10.3928/01913913-20100324-10.

Abstract

This study evaluated the outcome of corneal surface reconstruction with conjunctival limbal autograft and amniotic membrane transplantation in two children with unilateral ocular chemical burn who underwent surgery. Visual acuity improved from counting fingers at face to 20/60 in one patient and from counting fingers at 30 cm to 20/100 in the other. Both patients received simultaneous symblepharon lysis and regained deep fornices. When used in combination with amniotic membrane, conjunctival autograft allows correction of cicatricial abnormalities and early restoration of corneal surface integrity. Intervention within 6 months is desirable for rehabilitation of vision in the amblyogenic period.

摘要

本研究评估了两名接受手术的单侧眼化学烧伤儿童行结膜角膜缘自体移植联合羊膜移植进行角膜表面重建的效果。一名患者的视力从面部数指提高到20/60,另一名患者的视力从30厘米处数指提高到20/100。两名患者均同时进行了睑球粘连松解并恢复了深穹窿。结膜自体移植与羊膜联合使用时,可矫正瘢痕性异常并早期恢复角膜表面完整性。在弱视发生期,6个月内进行干预有利于视力康复。

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