Campsen Jeffrey, Zimmerman Michael A, Narkewicz Michael R, Sokol Ronald J, Mandell Mercedes S, Kam Igal, Dovel Diane, Karrer Frederick M
Department of Surgery, Division of Transplant Surgery, University of Colorado Denver School of Medicine, Aurora, CO, USA.
Pediatr Transplant. 2011 May;15(3):237-9. doi: 10.1111/j.1399-3046.2010.01338.x. Epub 2011 Jan 9.
Reconstruction of the bile ducts during pediatric liver transplantation is generally performed by a Roux-en-Y CDJ because direct duct-to-duct anastomosis CC is often not possible. Anastomosis of the donor liver bile duct to the duodenum CDD provides another option. We provide preliminary evidence that CDD is an alternative technique for biliary reconstruction when CC is not possible in pediatric liver transplant recipients that have a hostile abdomen or to preserve bowel length.
From 2007 to 2008, a total of 19 pediatric cadaveric liver transplants were performed at our center. Four of the 19 had a bile duct reconstruction by CDD.
CDD reconstruction was used in patients who received a liver transplant for a diagnosis of PSC, congenital hepatic fibrosis, biliary atresia, and Alagille syndrome. The ages of the patients were 17 and 10 yr and 10 and 17 months. Three grafts were whole cadaveric livers, and one was a reduced left lobe. CDD was used to revise a prior anastomosis in one patient who had a previous Roux-en-Y that was unusable during the retransplant, and another to repair a stricture in a second patient with a CC. We also performed a CDD in a patient with a hostile abdomen from previous surgery, and another patient to avoid short gut syndrome that a Roux-en-Y may have created. All patients are alive with functioning grafts with a follow-up of at least one yr. None of the patients developed clinically significant biliary complications (leak, stricture, cholangitis).
Our preliminary experience suggests that CDD is an option for biliary reconstruction in pediatric transplant patients with hostile abdomens or to preserve bowel length.
小儿肝移植术中胆管重建一般采用Roux-en-Y胆总管十二指肠吻合术(CDJ),因为胆管对端吻合术(CC)往往无法实施。供肝胆管与十二指肠吻合术(CDD)提供了另一种选择。我们提供的初步证据表明,对于腹部情况复杂或需保留肠管长度而无法进行CC的小儿肝移植受者,CDD是一种胆管重建的替代技术。
2007年至2008年,我们中心共进行了19例小儿尸体肝移植。其中19例中有4例采用CDD进行胆管重建。
CDD重建用于因原发性硬化性胆管炎、先天性肝纤维化、胆道闭锁和阿拉吉耶综合征而接受肝移植的患者。患者年龄分别为17岁和10岁,以及10个月和17个月。3例移植肝为全尸体肝,1例为左半肝缩小。1例曾行Roux-en-Y吻合术但再次移植时无法使用的患者,采用CDD对先前的吻合口进行修复;另1例CC吻合口狭窄的患者,也采用CDD进行修复。我们还对1例因既往手术导致腹部情况复杂的患者以及另1例为避免Roux-en-Y可能造成的短肠综合征的患者实施了CDD。所有患者均存活,移植肝功能良好,随访至少1年。所有患者均未发生具有临床意义的胆道并发症(渗漏、狭窄、胆管炎)。
我们的初步经验表明,对于腹部情况复杂或需保留肠管长度的小儿移植患者,CDD是胆管重建的一种选择。