围产期脑损伤后皮质运动代表区的转移。

Transfer of cortical motor representation after a perinatal cerebral insult.

机构信息

Department of Clinical Neurophysiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

出版信息

Pediatr Neurol. 2011 Feb;44(2):131-4. doi: 10.1016/j.pediatrneurol.2010.08.017.

DOI:10.1016/j.pediatrneurol.2010.08.017

PMID:21215913

Abstract

In a 16-year-old boy with hemiplegia and severe, intractable epilepsy after a neonatal cerebral ischemic insult, cortical motor control was only equivocally assessed by functional magnetic resonance imaging. Therefore, high-precision navigated transcranial magnetic stimulation was performed, which demonstrated that cortical control of muscles on the paretic side was selectively affected. Leg muscle control was located in the contralateral hemisphere, as expected in healthy individuals, whereas forearm muscles were controlled from both hemispheres, and hand muscles were controlled only from the hemisphere ipsilateral to the paresis.

摘要

在一名 16 岁男孩中，由于新生儿脑缺血性损伤导致偏瘫和严重、难治性癫痫，功能性磁共振成像仅能模糊地评估皮质运动控制。因此，进行了高精度导航经颅磁刺激，结果表明，瘫痪侧肌肉的皮质控制受到选择性影响。腿部肌肉控制位于对侧半球，这与健康个体的预期一致，而前臂肌肉则由两个半球控制，手部肌肉仅由瘫痪侧的半球控制。