Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY 14263, United States.
World J Gastroenterol. 2011 Jan 7;17(1):130-4. doi: 10.3748/wjg.v17.i1.130.
Duplication cyst of the stomach with a pseudostratified columnar ciliated epithelium is extremely rare. We describe two cases of these cysts, with emphasis on their immunophenotype and embryogenesis. The first patient was a 29-year-old man who presented with cramping abdominal pain in his left lower quadrant. The second patient was a 26-year-old woman who had a history, over several years, of chronic epigastric abdominal pain radiating to her back. Both lesions were surgically removed. They showed the same histomorphology. The cysts were lined by a pseudostratified respiratory epithelium with ciliated cells. The first cyst was connected to the stomach, while the second cyst was not connected. Both cysts expressed thyroid transcription factor-1 (TTF-1) and surfactant. In this report, we explore the possible embryogenesis of these lesions in the light of TTF-1 and surfactant expression.
胃重复囊肿伴假复层柱状纤毛上皮极为罕见。我们描述了两例这种囊肿，重点介绍其免疫表型和胚胎发生。第一例患者是一名 29 岁男性，表现为左下象限痉挛性腹痛。第二例患者是一名 26 岁女性，多年来一直有慢性上腹痛放射至背部。两个病变均通过手术切除。它们具有相同的组织形态学。囊肿由假复层呼吸上皮和纤毛细胞组成。第一个囊肿与胃相连，而第二个囊肿则不相连。两个囊肿均表达甲状腺转录因子-1（TTF-1）和表面活性剂。在本报告中，我们根据 TTF-1 和表面活性剂的表达探讨了这些病变的可能胚胎发生。
