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多发性骨髓瘤患者致死性粪类圆线虫重度感染。

Fatal Strongyloides stercoralis hyper-infection in a patient with multiple myeloma.

机构信息

Hematology Department, Al-Amal Hospital, Doha, QATAR.

出版信息

Braz J Infect Dis. 2010 Sep-Oct;14(5):536-9.

Abstract

Strongyloides stercoralis (S.S.) is a human intestinal parasite, which may lead to complicated strongyloidiasis. We report a case of disseminated strongyloidiasis following the treatment of myeloma. The patient developed skin lesions, respiratory distress, aseptic meningitis and bacterial and fungal sepsis. The diagnosis of strongyloidiasis was established through endotracheal tube secretions. Despite the treatment with Ivermectin and Albendazole, the outcome was fatal. The value of screening for strongyloidiasis is unclear but may be of benefit in patients with hematological malignancies from high endemic areas.

摘要

粪类圆线虫(S.S.)是一种人体肠道寄生虫,可能导致复杂的粪类圆线虫病。我们报告一例骨髓瘤治疗后播散性粪类圆线虫病。患者出现皮肤损伤、呼吸窘迫、无菌性脑膜炎和细菌及真菌感染性败血症。通过气管内管分泌物确诊为粪类圆线虫病。尽管使用伊维菌素和阿苯达唑治疗,但结局仍为致命性的。筛查粪类圆线虫病的价值尚不清楚,但对于来自高流行地区的血液恶性肿瘤患者可能有益。

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