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中性粒细胞在皮肤利什曼病中的作用。

Role of neutrophils in cutaneous leishmaniasis.

机构信息

Daboul Medical Laboratory, Damascus, Syrian Arab Republic.

出版信息

East Mediterr Health J. 2010 Oct;16(10):1055-8.

Abstract

Neutrophils are always present in the cytomorphologic process of leishmaniasis but their role is still not fully understood. Microscopic examination was done on smears from 56 cases of clinically diagnosed cutaneous leishmaniasis. Neutrophils were the predominant cells in the smear (> 35% of the total cell count including neutrophils, macrophages and lymphocytes) in 7% of cases, a minority (10%-35% of total cells) in 36% of cases and rare (< 10% of total cells) in 57% of cases. Microscope images confirmed that neutrophils appeared to have an important role in leishmania elimination through phagocytosis of amastigotes in the later stages of the disease process.

摘要

中性粒细胞始终存在于利什曼病的细胞形态学过程中,但它们的作用仍未完全阐明。对 56 例临床诊断为皮肤利什曼病的涂片进行了显微镜检查。在 7%的病例中,中性粒细胞是涂片(包括中性粒细胞、巨噬细胞和淋巴细胞在内的总细胞计数的>35%)中的主要细胞,在 36%的病例中是少数(总细胞的 10%-35%),在 57%的病例中是罕见的(总细胞的<10%)。显微镜图像证实,中性粒细胞似乎通过在疾病过程的后期吞噬无鞭毛体,在利什曼原虫的清除中发挥重要作用。

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