[Severe bradycardia and arterial hypotension following the administration of sublingual nitroglycerin].

Two patients with coronary artery disease who developed severe bradycardia (less than 40 beats/min) and hypotension (less than 65/...mmHg) in supine position following the administration of sublingual nitroglycerin in the course of an anginal pain are reported. The administration of intravenous atropine sulfate (1-1.5 mg) readily reverted both hypotension and bradycardia. In one patient this complication was observed three times; in this patient sublingual nifedipine (10 mg) was successfully used to treat subsequent anginal crisis.